Kornman KS(1), Löe H. Author information: (1)Department of Periodontics, University of Texas Health Science Center, San Antonio, USA. 1 Citations; 870 Downloads; Abstract. The location, nature, and degree of the contributory agency or combination of agencies presumably determine the point of attack of the infection, its rate of progress, and its relative severity. The main etiological factor is oral biofilm with microorganisms. Yuhan Huang, Dominique S. Michaud, Jiayun Lu, Elizabeth A. Platz, The association of clinically determined periodontal disease and edentulism with total cancer mortality: The National Health and Nutrition Examination Survey III, International Journal of Cancer, 10.1002/ijc.32941, 147, 6, … *Local contributing factors: are oral conditions that contribute to the disease progression. Plaque biofilm and calculus deposit. By continuing you agree to the use of cookies. Objectives. 74 terms. Destructive periodontal disease is a consequence of the interaction of genetic, environmental, host and micro- bial factors.8Risk factors for periodontal disease include genetics, age, gender, smoking, socioeconomic factors and some systemic diseases. The bacterial polysaccharides stimulate gingival neutrophils and macrophages to interleukin-1 (IL-1) production. Authors; Authors and affiliations; Thomas Thurnheer; Kai Bao; Georgios N. Belibasakis; Chapter. Inadequacy may be quantitative (the amount of the stimulus is excessive for the body), qualitative (the body is exposed to a factor for which it has not developed protective or … Community … 4. factors, since bacteria, which are considered as essential primary etiological factors of periodontal disease, will always be present in any individual to promote gingivitis1,2. 1993 Jun;2:83-97. Microbial plaque is the main etiological factor of periodontal disease. We use cookies to help provide and enhance our service and tailor content and ads. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Sources. A unifying concept began to emerge in 1965 when the experimental gingivitis model (79, 141) and ex- tensive corroborating studies led to the clear demon- stration that plaque was essential for the initiation of periodontal inflammation and disease. In advanced stages, periodontal disease can lead to sore, bleeding gums, painful chewing problems and even tooth loss. None of these factors seems to operate by itself. The bacterial polysaccharides stimulate gingival neutrophils and macrophages to interleukin-1 (IL-1) production. What faulty dentistry can be risk for periodontal disease? Subgingival Biofilms as Etiological Factors of Periodontal Disease. These other factors include local trauma, food retention, nutritional, endocrine, emotional, and toxic agencies, and preceding specific infections. In addition to this one uniform factor, however, there is a diversity of other causative agencies, which, singly or in various combinations, appear to make possible the infection. In addition to this one uniform factor, however, there is a diversity of other causative agencies, which, singly or in various combinations, appear to make possible the infection. n. 1. Eales' disease A non-specific peripheral retinal periphlebitis (i.e. Data. Female hormonal changes, such as with pregnancy or the use of oral contraceptives Rather any of them may contribute to the process by causing or aggravating a deviation from the ideal architectural balance of teeth and periodontium, leading to abnormal retention of microbic pabulum or to disturbances of local tissue resistance, or to both. 5. 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