For more details about the position and application process, please access this link: Call for Applications - Details. Multidisciplinary approach to dental and periodontal problems Section 7 - Supportive Treatment and Results of Treatment 69. We'll do our best to fix them. Goodson, JM; Tanner, A; McArdle, S; Dix, K; Watenable, SM. Author information: (1)Division of Periodontology, Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA, USA. Periodontol disease as we approach the year 2000. Supportive periodontal treatment 70. DeepDyve's default query mode: search by keyword or DOI. Following completion of treatment and arrest of inflammation, supportive periodontal therapy (SPT) is employed to reduce the probability of re-infection and progression of the disease; to maintain teeth without pain, excessive mobility or persistent infection in the long term, and to prevent related oral diseases.According to the American Academy of Periodontology, SPT should include all components of a typical dental recall examination, and importantly should also include periodontal … PERIODONTOLOGY,2000, Acute,gingival,and,periodontal,lesions,, David&Herrera,&BettinaAlonso,&Lorenzo&de&Arriba,&Isabel&SantaCruz,&CristinaSerrano,& Part I. All the latest content is available, no embargo periods. The infection triggers host inflammatory responses resulting in the destruction of the tooth supporting tissues. Clinical and microbiological findings that may contribute to dental implant failure. A review of the literature with possible applications to periodontics. Submitting a report will send us an email through our customer support system. Read and print from thousands of top scholarly journals. 1! 1996; 2000 (12):129-132 Enjoy affordable access to All DeepDyve websites use cookies to improve your online experience. You can change your cookie settings through your browser. Periodontology 2000. Westfeld, E; Nyman, S; Socransky, S; Lindhe, J. The importance of periodontal maintenance for the dental implant, Land HP? that matters to you. A 14âyear retrospective study, Demetriou, N; TsamiâPandi, A; Parashis, A, Retrospective evaluation of patients compliance with supportive periodontal treatment, Intervention for replacing missing teeth: maintaining and reâestablishing healthy tissues around dental implants (Cochrane review), Esposito, M; Worthington, HW; Coultard, P; Jokstad, A, The effect of a triclosan/copylymer dentifrice on healing after nonâsurgical treatment of recurrent periodontitis, Furuichi, Y; Rosling, B; Volpe, AR; Lindhe, J, Patterns of progression and regression of advanced destructive periodontal disease, Goodson, JM; Tanner, ACR; Haffajee, AD; Sornberger, GC; Socransky, SS, Prevalence and extent of lifetime cumulative attachment loss (LCAL) at different thresholds and associations with clinical variables: changes in a population of young male military recruits over 3 years, Griffiths, GS; Duffy, S; Eaton, KA; Gilthorpe, MS; Johnson, NW, Evidence for cigarette smoking as a major risk factor for periodontitis, Haber, J; Wattles, J; Crowley, M; Mandell, R; Joshipura, K; Kent, R, Local delivery of chlorhexidine gluconate (PerioChip) in periodontal maintenance patients, Heasman, PA; Heasman, L; Stacey, F; McCracken, GI, Supportive periodontal care: The effect of periodic subgingival debridement compared with supragingival prophylaxis with respect to clinical outcomes, The effect of supraâgingival plaque control on the subâgingival microflora in human periodontitis, Hellström, MK; Ramberg, P; Krok, L; Lindhe, J, Granulocyte elastase in gingival crevicular fluid: improved monitoring of the siteâspecific response to treatment in patients with destructive periodontitis, Jin, LJ; Söder, PâO; Ã
sman, B; Bergström, K, Variations in crevicular fluid elastase levels in periodontitis patients on longâterm maintenance, Jin, LJ; Söder, PâO; Ã
sman, B; Söder, B; Purliene, A; Bergström, K, Effect of subgingival scaling during supportive therapy, Jenkins, WM; Said, SH; Radvar, M; Kinane, DF, Evaluation of cause related periodontal therapy and compliance with maintenance care recommendations, The effects of subgingival calculus on the clinical outcomes of locallyâdelivered controlledârelease doxycycline compared to scaling and root planning, Johnson, RL; Stoller, NH; Polson, A; Harrold, CQ; Ryder, M; Garrett, S, Bleeding on probing. that matters to you. It is generally agreed that periodic supportive periodontal therapy (SPT) is important for the maintenance of periodontal health after active periodontal treatment. Enjoy affordable access to 2. Read "Supportive periodontal therapy, Periodontology 2000" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Journal of Clinical Periodontology Vol. Maintenance care is mandatory for the long-term success of periodontal and implant treatment. Thus, at untreated tooth sites, clinical measures of oral hygiene, gingivitis, pocket probing depths, and clinical attachment levels were poor predictors of disease activity over 18 months ( 87 ). Periodontal research: exploring new horizons. Several recent investigations have demonstrated the significance of host specific factors that can either contribute to the exacerbation of periodontitis or effectively control the infection. Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals. Greenstein, G; Polson, AM; Iker, H; Meitner, S. Histologic characteristics associated with bleeding after probing and visual signs of inflammation, A contemporary perspective on techniques for the clinical assessment of alveolar bone, Current Concepts in periodontal disease testing, Extraoral control of geometry for digital subtraction radiography. Of upmost importance is the patien … Supportive periodontal therapy. The effectiveness of clinical parameters and ILâ1 genotype in accurately predicting prognosis and tooth survival, Studies of dental root surface caries. • Hancock EB. Diagnostic characteristics of crevicular fluid aspartate aminotransferase (AST) levels associated with periodontal disease activity, Access to subgingival plaque by disclosing agents using mouth rinsing and direct irrigation, Gingival augmentation/mucogingival surgery, Doctors talking with patientslpatients talking with doctors, Calcium channel blockers and gingival overgrowth, Rapid identification of important periodontal microorganisms by cultivation, Levels of interleukin 1b in tissue from sites of active periodontal disease. Author T D Rees 1 Affiliation 1 Department of Periodontics ... periodontal therapy is rendered and the patient maintains effective oral hygiene measures accompanied by appropriate supportive periodontal recall therapy. Risk of nonâcompliance in a 10âyear period, Supportive periodontal therapy in South America. The Cochrane Database of Systematic Reviews. Periodontal treatment consists of active periodontal therapy (APT) and supportive periodontal therapy (SPT). Based on their compliance with the recommended schedule of visits, the patients were classified as either compliant or non‐compliant. Supportive Periodontal Therapy (SPT) Following completion of the active phase of periodontal treatment, a personalized program of supportive periodontal treatment will help you maintain periodontal health. Martin et al 11 did a cost-effectiveness analysis of periodontal treatment vs a three-unit bridge or single tooth replacement. Weitzman, SA; Weithery, AB; Niederman, R; Stossel, TP, Significance of professional tooth cleaning for healing following periodontal surgery. Consequences of no treatment should be explained. [Google Scholar] Lang N. P., Adler R., Joss A. Bjorn technique. – Wiley. Neither the infection nor the host's inflammatory responses are completely understood. Unlimited access to over18 million full-text articles. Jeffcoat, MK; Reddy, MS; Webber, RL; Williams, R; Rutteimann, W. Progression of probing attachment loss in adult periodontitis, Electronic compliance monitoring in clinical trials, Controlled local delivery of tetracy cline in treatment of periodontitis, Long term maintenance of patients treated for advanced periodontal disease, Comparative differential darkfield microscopy of subgingival bacteria from tooth surfaces with recent evidence of recurring periodontitis and from non‐affected surfaces. Supportive periodontal therapy. Periodontal diagnosis and diagnostic aids, A longitudinal study of aspartate aminotransferase in human crevicular fluid, Contaminated implant surfaces: an in vitro comparison of implant surface coating and treatment modalities for decontamination. 5âyear observations in general dentistry patients, Rosen, B; Olavi, G; Badersten, A; Rönström, A; Söderholm, G; Egelberg, J, Longitudinal periodontal tissue alterations during supportive therapy. Trustees in approving the term “periodontal mainte-nance” in lieu of “supportive periodontal therapy” (Jan-uary 2000) and a new classification of periodontal dis-eases, as published in the Annals of Periodontology, December 1999; Volume 4, number 1 (April 2000). A review. Include any more information that will help us locate the issue and fix it faster for you. Bookmark this article. The microbiota associated with successful or failing osseointegrated ticonium implants, A six month multicenter evaluation of adjunctive tetracycline fiber therapy used in conjunction with scaling and root planing in maintenance patients – clinical results. termed maintenance is called as Supportive Periodontal Therapy (SPT) according to 5th American Academy of Periodontology (AAP), 1986.6 In 1989 the World Workshop in Clinical Periodontics described by the term ‘supportive periodontal treatment’ (SPT).7 In 2003 AAP, position paper termed as Periodontal Maintenance Therapy.8 Renvert S, Persson GR. A retrospective study of 44 patients. You can see your Bookmarks on your DeepDyve Library. over 18 million articles from more than The primary objective of this study was to assess the association between tooth loss and the non‐surgical periodontal treatment history of 1,021 members of the Kaiser Permanente Dental Care Program. Stephenson, BJ; Rowe, BH; Haynes, B; Macharia, WM; Leon, G. Noncompliance with medications: an economic tragedy with important implications for health care reform, Zero‐order delivery with periodontal placement of tetracycline loaded ethylene vinyl acetate fibers, The interdental brush and its place in operative crown and bridge dentistry, Dental plaque removal by cavitational activity during ultrasonic scaling, Effects of cavitational activity on the root surface of teeth during ultrasonic scaling. III. Associations between crestal lamina dura and periodontal status. Di Wu, Hai Jing Yang, Yan Zhang, Xiu E. Li, Yu Rong Jia, Chun Mei Wang, Prediction of loss to follow-up in long-term supportive periodontal therapy in patients with chronic periodontitis, PLOS ONE, 10.1371/journal.pone.0192221, 13, 2, (e0192221), (2018). • Wilson TG Jr. 15,000 peer-reviewed journals. Itâs your single place to instantly I. Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more. Chronic periodontitis is an infectious disease caused by an opportunistic microflora. Different modalities, Kaldahl, WB; Kalkwarf, KL; Patil, KD; Molvar, MP; Dyer, JK, Pain experienced by patients during periodontal maintenance treatment, Karadottir, H; Leonir, L; Barbierato, B; Bogle, M; Riggs, M; Sigurdsson, T; Crigger, M; Egelberg, J, Disease progression in periodontally treated and untreated patients â a retrospective study, Kocher, T; König, J; Dzierzon, U; Sawaf, H; Plagmann, HC, Retrospective comparison of clinical variables between compliant and nonâcompliant patients, König, J; Plagmann, HC; Langenfeld, N; Kocher, T, The interleukinâ1 genotype as a severity factor in adult periodontal disease, Kornman, KS; Crane, A; Wang, HY; Di Giovine, FS; Newman, MG; Pirk, FW; Wilson, TG; Higginbottom, FL; Duff, GW, Periodontal risk assessment (PRA) for patients in supportive periodontal therapy, Effect of interleukinâ1 gene polymorphisms on gingival inflammation assessed by bleeding on probing in a periodontal maintenance population, Lang, NP; Tonetti, MS; Suter, J; Sorrell, J; Duff, GW; Kornman, KS, Survival of BrÃ¥nemark in partially edentulous jaws: a 10 year prospective multicenter study, Lekholm, U; Gunne, J; Henry, P; Higuchi, K; Linden, U; Berström, C; Van Steenberghe, D, 5âyear clinical microbiological and radiological outcome following treatment of periâimplantitis in man, Periodontal loser sites in untreated adult subjects, Lindhe, J; Okamoto, H; Yoneyama, T; Haffajee, A; Socransky, SS, Longâterm effect of surgical/nonâsurgical treatment of periodontal disease, Lindhe, J; Westfelt, E; Nyman, S; Socransky, SS; Haffajee, AD, The nonsurgical treatment of patients with periodontal disease: results after five years, Loesche, WJ; Giordano, JR; Soehren, S; Kaciroti, N, Recolonization of subgingival microbiota following scaling in deep pockets, Magnusson, I; Lindhe, J; Yoneyama, T; Liljenberg, B, Prognosis versus actual outcome III. Recall intervals for oral health in primary care patients. 's ( 87 ) study demonstrated that a majority of untreated sites (approximately 75%) experienced no progression of disease or improved in the absence of care. Dennison, DK; Huerzeler, MB; Quiñones, CR. Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more. In fact, Reddy et al. A 5âyear longitudinal study, Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial, Williams, R; Paquette, D; Offenbacher, S; Adams, DF; Armitage, GC; Bray, K; Caton, J; Cochran, DL; Drisko, CH; Fiorellini, JP; Giannobile, WV; Grossi, S; Guerrero, DM; Johnson, GK; Lamster, IB; Magnusson, I; Oringer, RJ; Persson, GR; Van Dyke, TE; Wolff, LF; Santucci, EA; Rodda, BE; Lessem, J, Compliance and its role in periodontal therapy, Renvert, Stefan, and G. Rutger Persson. Supportive periodontal therapy, Periodontology 2000 | 10.1111/j.1600-0757.2004.03680.x | DeepDyve. Sarah K. Sonnenschein, Rebecca Kohnen, Maurice Ruetters, Johannes Krisam, Ti‐Sun Kim, Adherence to long‐term supportive periodontal therapy in groups with different periodontal risk profiles, Journal of Clinical Periodontology, 10.1111/jcpe.13252, 47, 3, (351-361), (2020). Select data courtesy of the U.S. National Library of Medicine. A retrospective study in 44 patients, A longitudinal study comparing scaling, osseous surgery, and modified Widman procedures: Results after 5 years, Becker, W; Becker, B; Caffesse, R; Kerry, G; Ochsenbein, C; Morrison, E; Prichard, J, A 5âyear study of attachment loss and tooth loss in communityâdwelling older adults, Beck, JD; Sharp, T; Koch, GG; Offenbacher, S, Treatment of periâimplantitis defects with autogenous bone grafts: 6âmonth to 3âyear results of a prospective study in 17 patients, Cigarette smoking as a risk factor in chronic periodontal disease, Cigarette smoking and periodontal bone loss, Influence of smoking on the outcome of periodontal surgery, Periodontal conditions in 65â74 year old adults in France, Actinobacillus actinomycetemcomitans in destructive periodontal disease. Require these words, in this exact order. IV. French, CK; Savitt, ED; Simon, SL; Erklund, SM; Chen, ME; Klotz, LC; Vaccaro, KK. Siddharth Shanbhag, Manu Dahiya, Ray Croucher, The impact of periodontal therapy on oral health‐related quality of life in adults: a systematic review, Journal of Clinical Periodontology, 10.1111/j.1600-051X.2012.01910.x, 39, 8, (725-735), (2012). Microbiological response. Diagnosis and management of mucogingival problems in children, Clinical and anti microbial effect of stannous fluoride periodontitis. Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly. • Renvert S. Supportive periodontal therapy. Copy and paste the desired citation format or use the link below to download a file formatted for EndNote. Unlimited access to over18 million full-text articles. Read and print from thousands of top scholarly journals. Wiley is seeking an Editor-in-Chief for Periodontology 2000 to serve an initial three-year term. Like any other chronic disease, periodontal disease can be treated, but not eradicated. Sarah K. Sonnenschein, Rebecca Kohnen, Maurice Ruetters, Johannes Krisam, Ti‐Sun Kim, Adherence to long‐term supportive periodontal therapy in groups with different periodontal risk profiles, Journal of Clinical Periodontology, 10.1111/jcpe.13252, 47, 3, (351-361), (2020). Goodson, JM; Cugini, MA; Kent, RL; Armitage, GC; Cobb, CM; Fine, D; Fritz, ME; Green, E; Imoberdord, MJ; Killoy, WJ; Mendicta, C; Niederman, R; Offenbacher, S; Taggart, EJ; Tonetti, M. Multicenter evaluation of tetracycline fiber therapy. The relationship between attachment level loss and alveolar bone loss. Search Include any more information that will help us locate the issue and fix it faster for you. 11 They found that the cost of periodontal treatment divided by the number of teeth preserved ranged from $1,405 to $4,895 for patients at high and moderate risk combined with severity of chronic periodontitis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png, http://www.deepdyve.com/lp/wiley/supportive-periodontal-therapy-V0AmAUchAF. This suggests that the evaluation of the efficacy of supportive periodontal therapy (SPT) must be carried out over an extended period of time. Temperature differences at sites in health and disease, A 10 year longi tudinal study of untreated mucogingival defects. Thanks for helping us catch any problems with articles on DeepDyve. However, in recent years the mass media have helped to increase knowledge of this chronic disease. Listgarten, MA; Levin, S; Schifter, CC; Sullivan, P; Evian, C; Ro senberg, ES. ISSN 0906-6713 Manual periodontal probing i n supportive periodontal treatment GARY ARMITAGE C. Although straight steel probes were in widespread use by dentists in the early 19OOs, they were primarily used for identifymg the origin and extent of periodontal abscesses (12). 2013 Feb;61(1):16-53. doi: 10.1111/j.1600-0757.2011.00397.x. This trend started in the 1960s and is continuing into the 1990s. Search Submitting a report will send us an email through our customer support system. Read "Supportive periodontal treatment, Periodontology 2000" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. Periodontal disease is an infection of the … Twenty or more years ago, 50% of the individuals 65 years or older living in the United States were edentulous (7). Trends in tooth loss among U.S. employed adults from 1971 to 1985. The application deadline is December 15, 2020. Chronic periodontitis is an infectious disease caused by an opportunistic microflora. Find any of these words, separated by spaces, Exclude each of these words, separated by spaces, Search for these terms only in the title of an article, Most effective as: LastName, First Name or Lastname, FN, Search for articles published in journals where these words are in the journal name, /lp/wiley/supportive-periodontal-treatment-P9HfJivHYi, The significance of maintenance care in the treatment of periodontal disease. We'll do our best to fix them. "Supportive periodontal therapy.". Check all that apply - Please note that only the first page is available if you have not selected a reading option after clicking "Read Article". To maintain periodontal stability, these treatments need to be supplemented with long-term maintenance (supportive periodontal therapy) programs. Patrícia Daniela Melchiors Angst, Amanda Finger Stadler, Marina Mendez, Rui Vicente Oppermann, Ubele van der Velden, Sabrina Carvalho Gomes, Supportive periodontal therapy in moderate‐to‐severe periodontitis patients: A two‐year randomized clinical trial, Journal of Clinical Periodontology, 10.1111/jcpe.13178, 46, 11, (1083-1093), (2019). A caseâcontrol study, Papapanou, PN; Neiderud, AM; Sandros, J; Dahlén, G, Periodontal effects of a bioâbehavioral prevention program, Persson, RE; Persson, GR; Powell, LV; Kiyak, HA, A multiâcenter clinical trial of Periogard in distinguishing between diseased and healthy periodontal sites. We are witnessing a remarkable change in oral health in the United States. II. No longer is it expected or anticipated that âgrannyâ will order her false teeth from a Sears Roebuck catalogue. Untreated chronic periodontitis has been described as a slowly progressive disease affecting individual teeth or tooth sites, showing evidence of periods of stability and periods of progression ( 32, 55 ). A ll new patients commencing supportive periodontal therapy (periodontal maintenance) after treatment in a specialist periodontal practice from 1983 to 1986 were identified from practice records. Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place. Periodontology 2000, vol. Impact of Patient Compliance on Tooth Loss during Supportive Periodontal Therapy: A Systematic Review and Meta-analysis. Goodson, JM; Cugini, MA; Kent, RL; Armitage, GC; Cobb, CM; Fine, D; Fritz, ME; Green, E; Imoberdorf, MJ; Killoy, WJ; Mendicta, C; Niederman, R; Offenbacher, S; Taggart, EJ; Tonetti, M. Multicenter evaluation of tetracycline fiber therapy. Woong-Kyu Park, Jae-Kwan Lee, Beom-Seok Chang, Heung-Sik Um, A retrospective study on patients' compliance with supportive periodontal therapy, The Journal of the Korean Academy of Periodontology, 10.5051/jkape.2009.39.1.59, 39, 1, (59), (2009). ISSN 0906-6713 Supportive periodontal treatment GLORIA JAMES KERRY Preventive dental care is allowing increasing proportions of the population in industrialized countries in all age brackets to maintain their teeth for their lifetime. – Wiley. To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one. Is this patient taking the treatment as prescribed? Findings from subjects with normal and high susceptibility to periodontal disease, Rosling, B; Serino, G; Hellström, MK; Socransky, SS; Lindhe, J, The use of a triclosan/copolymer dentifrice may retard progression of periodontitis, Rosling, B; Wannfors, B; Volpe, AR; Furuchi, V; Ramberg, P; Lindhe, J, Interleukinâ1 gene polymorphisms and longâterm stability following guided tissue regeneration therapy, Recolonization of the subâgingival microflora after scaling and root planing in human periodontitis, Sbordone, L; Ramaglia, L; Gulletta, E; Iacono, V, The longâterm effect of systemic tetracycline used as an adjunct to nonâsurgical treatment of advanced periodontitis, Serino, G; Rosling, B; Ramberg, P; Hellström, MK; Socransky, SS; Lindhe, J, A clinical and radiological 2âyear followâup study of maxillary overdentures on osseointegrated implants, Smedberg, JI; Lothigius, E; Frykholm, A; Nilner, K, Subgingival microbial profiles in refractory periodontal disease, Clinical evaluation of cervical dentin sensitivity (CDS) in patients attending general dental clinics (GDC) and periodontal specialty clinics (PSC), Rootâdentin sensitivity following nonâsurgical periodontal treatment, Tammaro, S; Wennström, JL; Bergenholtz, G, ILâ1 genotype and adult periodontitis among young New Zealanders, Thomson, WM; Edwards, SJ; DobsonâLe, DP; Tompkins, GR; Poulton, R; Knight, DA; Braithwaite, AW, Changes in the prevalence of residual pockets and tooth loss in treated periodontal patients during a supportive maintenance care program, Tonetti, MS; MullerâCampanile, V; Lang, NP, Initial extractions and tooth loss during supportive care in a periodontal population seeking comprehensive care, Tonetti, MS; Steffen, P; MullerâCampanile, V; Suvan, J; Lang, NP, Persistent presence of Bacteroides forsythus as a risk factor for attachment loss in a population with low prevalence and severity of adult periodontitis, Tran, SD; Rudney, JD; Sparks, BS; Hodges, JS, Clinical, genetic and microbiological findings in a Brazilian family with aggressive periodontitis, Trevilatto, PC; Tramontina, VA; Machado, MA; Goncalves, RB; Sallum, AW; Line, SR, Mutans streptococci in subgingival plaque of treated and untreated patients with periodontitis, Van der Reijden, WA; DellemijnâKippuw, N; Stijneâvan Nes, AM; De Soet, JJ; Van Winkelhoff, AJ, Periodontal indices around natural teeth and titanium abutments: a longitudinal multiâcenter study, Van Steenberghe, D; Klinge, B; Linden, U; Quirynen, M; Herrmann, I; Garpland, C, The applicability of osseoâintegrated oral implants in the rehabilitation of partial edentulism: a prospective multiâcenter study on 558 fixtures, Van Steenberghe, D; Lekholm, L; Bolender, C; Folmer, T; Henry, P; Herrmann, I; Higuchi, K; Laney, W; Linden, U; Ã
strand, P, Microbial succession in recolonizing deep periodontal pockets after a single course of supraâ and subgingival debridement, Van Winkelhoff, AJ; Van Der Velden, U; De Graaff, J, Radiographic evaluation of crestal bone levels adjacent to nonâsubmerged titanium implants, Healing following surgical and nonâsurgical treatment of juvenile periodontitis. Keyword or DOI it faster for you that are performed at selected intervals to assist the periodontal patient in oral! ; Quiñones, CR tooth replacement dental root surface caries Moles D. R. ( 2005 ) review.: a Systematic review and Meta-analysis can see your Bookmarks on your DeepDyve.... Mucogingival problems in children, clinical and microbiological findings that may contribute to supportive periodontal therapy periodontology 2000 implant, Land HP smoking nonsurgical. ; Wikström, M ; Slots, J:16-53. 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